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Transcriptomic Signature Related to Poor Welfare of Sport Horses

Transcriptomic Signature Related to Poor Welfare of Sport Horses

A 2023 study identifies blood‑based gene expression patterns linked to behavioral indicators of poor welfare in sport horses, including aggressiveness and stereotypies.

Researchers analyzed the blood transcriptome of 45 individually housed sport horses and found strong correlations between gene expression and behavioral signs of compromised welfare. Aggressiveness toward humans showed the strongest association with inflammatory pathways, while stereotypies also aligned with distinct gene expression profiles when combined with microbiota data. The study highlights potential biomarkers for identifying horses experiencing poor welfare and underscores the physiological impact of management practices.